The differences will evaporate slowly ... until we’re all computers
It’s just very hard to even try to make the comparison.
PLs don't use bidirectional communication: they do not involve interchangeability between the speaker and hearer
PLs do not have ‘duality of patterning’ meaning multiple layers of structure as sounds vs. phrases (phonology vs. syntax), and are not transmitted culturally (well, maybe)
They’re completely distinct in being written only